Karen A. Beitler
DNA & RNA Webquest
Website;
www. dnaftb.org
- click on
Molecules of Genetics
On the right side you will see chapter numbers they will be displayed 15 to show you where to find the information to fill in the blanks.
15 Read the introduction then click on Animation
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1. Who isolated nuclein from cells? _________________________________
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2. What did he do to isolate it? __________________________________
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3. What did he think it was? _______________________________________
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4. What did Phoebus Levene find? __________________________________
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5. What are proteins made up of? __________________________________
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6. What are the 4 subunits of DNA called? __________________
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7. What are they made up of? _____________________________________
Click on Problem write the answers here:
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17 A Gene is made of DNA
What is the transforming principle? ________________________
Click on Audio/Visual. Click on gene - write the definition here ____________________________________________________Click on [X]
19 The DNA molecule is shaped like a _________ ___________ what is it composed of? ______________________________________________
Click on Animation
James __________ and Frances _________ found that ________ _______ are linked in a series. Erwin __________ isolated DNA from different organisms and measured the levels of each of four ______________ _______. He found that the amount of adenine was close to the amount of ___________ and the amount of cytosine was approximately as much as ____________. At Cal Tech, Linus _________ used X-ray crystallography to discover the _______ ________. Rosalind __________ and Maurice __________ made DNA X-ray ______________ patterns and were able to calculate the basic ________________ of the DNA molecule. Frances Click found that there must be _____ nucleotides between each helical repeat. From the X-ray diffraction pattern, Click deduced DNA should be a __________ __________
With phosphate groups on the outside and __________ on the inside. James Watson found that the ______ base pair was about the same width as the G/C _______ pair. Guanine makes _____ hydrogen bonds with ___________ and adenine makes 2 ___________ bonds with thymine. Therefore, DNA is like a twisted _____________ where the _________ and _______________ are the rails and the base _________ are the rungs. The rails run in __________
orientation to each other. Wherever there is a __________ on one strand there is a thymine on the other strand. Similarly, wherever there is a cytosine there is a _________ on its opposite strand.
What was the concluding statement in Watson and Clicks 900 word statement on the structure of DNA? Write it here__________________________
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Watson and Crick proposed that one half of the DNA ladder serves as a template for recreating DNA. What did the experiment using nitrogen isotopes show? _______________________________________________________
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Describe the "central dogma" of genetic information.
Click on Animation
Name three differences between DNA & RNA
DNA RNA
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Paul _____________ was interested in _____________ ______________. He made an extract using rat liver cells, added radio labeled _________ _____, incubated and centrifuged them. He identified a large cellular structure later named the ____________, where protein assembly occurs. Mahlon ________ found amino acids were activated by __________. With Mary ____________ he found a low molecular weight "soluble" RNA later named transfer RNA. Sydney _________, Francois _______, Mathew ____________ shower there was a third type of RNA that carries the DNA message to the ribosome. Using phase-infected bacteria, they found that one ribosome is made up of _______. The larger of which was the heavier RNA, the carrier called __________
Click on Problem
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22 DNA words are three letters long. A three letter code is called a ______
Click on Problem